Week 5 College Football Betting Splits Systems and Picks:

CFB DK Betting Splits system #1: Going back to the start of the 2022 season, when more than 75% of the handle was on a particular side of an ATS wager, this majority group has gone just 626-688 ATS (47.6%).
System Matches (FADE ALL): MEMPHIS, HOUSTON, MIDDLE TENNESSEE STATE, NOTRE DAME, GEORGIA, WESTERN MICHIGAN, TOLEDO, CENTRAL MICHIGAN, OHIO, MIAMI (OH), FLORIDA, LOUISVILLE, TENNESSEE, UNLV, NORTH DAKOTA STATE, UMASS, JAMES MADISON, NEW MEXICO, PURDUE, UTSA, BYU, TEXAS A&M, GEORGIA SOUTHERN, SOUTH ALABAMA, BOISE STATE, TEMPLE, USC, LA LAFAYETTE, FRESNO STATE, TEXAS STATE

CFB DK Betting Splits system #2: When 76%+ of the number of bets were on the home side of an ATS wager since the start of the 2022 season, this majority group has gone just 272-290 ATS (48.4%). In 2022 it was 46.5%, in 2023 it was 46.7%, in 2024 it was 46.6%.
System Matches (FADE ALL): HOUSTON, GEORGIA, MIAMI (OH), TENNESSEE, NORTH DAKOTA STATE, UMASS, GEORGIA STATE, JAMES MADISON, NEW MEXICO, BOISE STATE, USC, LA LAFAYETTE

CFB DK Betting Splits system #3: When the majority of the handle was on road favorites for an ATS wager since the start of the 2022 season, this majority group is just 389-431 ATS (47.4%).
System Matches (FADE ALL): MEMPHIS, SYRACUSE, NOTRE DAME, WESTERN MICHIGAN, TOLEDO, OHIO STATE, OHIO, FLORIDA, LOUISVILLE, OREGON STATE, UTSA, BYU, GEORGIA SOUTHERN, MIAMI (FL), TEXAS TECH, ARMY, TEXAS STATE

CFB DK Betting Splits system #4: When a 68%+ majority of the handle was on small home favorites of 7 points or fewer for an ATS wager since the start of the 2023 season, this majority group is 87-71 ATS (55.1%).
System Matches (PLAY ALL): CHARLOTTE, CENTRAL MICHIGAN, TENNESSEE, UNLV, UMASS, LA LAFAYETTE, ARIZONA

CFB DK Betting Splits system #5: When a 58% or greater majority of the handle has been on road underdogs for an ATS wager since the start of the 2022 season, this majority group has gone 165-148-2 ATS (52.7%).
System Matches (SLIGHT PLAY ALL): MIDDLE TENNESSEE STATE, STANFORD, MICHIGAN STATE, PURDUE, TEMPLE, FRESNO STATE, SAN JOSE STATE

CFB DK Betting Splits system #6: When a majority of 55% or more of number of bets has backed road underdogs for an ATS wager over the past four seasons, this majority group has gone 161-141-1 ATS (53.3%).
System Matches (SLIGHT PLAY ALL): FRESNO STATE, BAYLOR

CFB DK Betting Splits system #10: Since the start of the 2022 season, on games with totals of 49 or lower, 72%+ super majority handle bettors siding with the Under have gone 72-59 (55%).
System Matches (PLAY UNDER ALL): MICHIGAN-MINNESOTA, WYOMING-NORTH DAKOTA STATE, BYU-TCU, TEMPLE-SOUTH FLORIDA, FRESNO STATE-WASHINGTON STATE, BAYLOR-ARIZONA STATE

CFB DK Betting Splits system #11: Since the start of the 2022 season, on games with totals of 46.5 or lower, 72%+ super majority number of bets bettors bucking the low total and siding with the Over have gone 216-183 (54.1%).
System Matches (PLAY OVER ALL): NOTRE DAME-NORTH CAROLINA, MICHIGAN STATE-WISCONSIN, WESTERN MICHIGAN-BUFFALO, OHIO STATE-IOWA, BOWLING GREEN-MIAMI (OH), WYOMING-NORTH DAKOTA STATE, ARMY-LOUISIANA TECH

CFB DK Betting Splits system #12: Since the start of the 2022 season, majority handle bettors have been quite sharp in two different contrarian ways for betting totals in non-conference games. When greater than 80% majorities have gotten behind Overs for totals of less than 55, they’ve gone 67-37 (64.4%).
System Match (PLAY OVER): ARMY-LOUISIANA TECH

For more Week 5 college football best bets, visit the Week 5 College Football Hub, exclusively at VSiN.com.

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Steve Makinen
As one of the original founders of StatFox, Steve Makinen has been in the business of sports betting and data analysis for almost 25 years now. In his time in the industry, Steve has worked in a variety of capacities on both sides of the betting counter, from his early days of developing the StatFox business, to almost a decade of oddsmaking consulting for one of the world's leading sportsbooks, to his last seven years as Point Spread Weekly and Analytics Director with VSiN. Steve has always believed that number crunching and handicapping through foundational trends and systems is the secret to success and he shares this data with VSiN readers on a daily basis for all of the major sports.