MLB Picks Today:
Expert baseball handicapper Greg Peterson shares his top MLB picks today for Wednesday, March 25.
Check out Greg’s Daily MLB Lines and his Baseball Betting Show Podcast. Also, check out our MLB Betting Splits and tools from our friends at Ballpark Pal, including Strikeout Prop Projections and the MLB YRFI Report.
8:00 PM Eastern
New York Yankees vs. San Francisco Giants
Giants starting pitcher Logan Webb has always had large home and road splits, posting for his career a 2.84 ERA with 0.5 home runs per nine innings at home compared to a 3.95 ERA on the road with nearly 0.8 home runs per nine innings allowed. However, he saw his ERA at home jump to 3.10 last season, the highest it has been since 2020.
While Yankees starter Max Fried was shaky late in the 2025 regular season, he has traditionally been a strong early-season starter with a lifetime 3.01 ERA and just over 0.7 home runs per nine innings allowed in the months of March and April. He also has the support of a Yankees lineup that returns most of last season’s core after leading the league with 5.2 runs per game.
Pick: Yankees -114 and Over 7 Runs
Greg’s Handicap: Yankees -133 and Total 7.26
