MLB Picks Today:

Expert baseball handicapper Greg Peterson shares his top MLB picks today for Monday, May 26.

Check out Greg’s Daily MLB Lines and his Baseball Betting Show Podcast. Also, check out our MLB Betting Splits.

 

3:05 PM Eastern

St. Louis Cardinals vs. Baltimore Orioles

Cardinals starting pitcher Erick Fedde owns a 3.77 ERA with 0.8 home runs allowed per nine innings and faces an Orioles lineup that entered Sunday ranked 25th in the league in scoring, averaging just over 3.8 runs per game. Orioles starting pitcher Charlie Morton has a 7.86 ERA with 2.0 home runs and 5.3 walks allowed per nine innings.

Pick: Cardinals Moneyline -104 (Greg’s Handicap: Cardinals -144)

4:10 PM Eastern

Cincinnati Reds vs. Kansas City Royals

Royals starting pitcher Michael Lorenzen owns a 3.77 ERA with 1.4 home runs allowed per nine innings, but he’s backed by a bullpen that ranks fifth in bullpen ERA at 3.27. Reds starter Nick Martinez has a 3.43 ERA with just 0.6 home runs allowed per nine innings, though that ERA climbs to 4.18 on the road. The Reds’ overall team ERA of 4.11 ranks 18th.

Pick: Royals Moneyline -116 (Greg’s Handicap: Royals -134)

Chicago White Sox vs. New York Mets

White Sox starter Adrian Houser dazzled in his first MLB start of the season, tossing six shutout innings. Mets starter Clay Holmes draws a favorable matchup against a White Sox lineup that ranks 28th in scoring at 3.3 runs per game — a number that dips to 2.9 on the road. Holmes enters with a 3.13 ERA and just 0.8 home runs allowed per nine innings.

Pick: Under 8.5 Runs (Greg’s Handicapped Total: 7.6)

7:05 PM Eastern

Minnesota Twins vs. Tampa Bay Rays

Twins starter Chris Paddack has allowed three earned runs or fewer in nine straight starts, posting a 2.22 ERA across his last eight. Rays starter Zack Littell holds a 4.25 ERA, but an inflated 5.42 fielding independent and 2.1 home runs allowed per nine innings.

Pick: Twins Moneyline +108 (Greg’s Handicap: Twins -111)

9:38 PM Eastern

New York Yankees vs. Los Angeles Angels

Angels starter Jack Kochanowicz owns a 5.03 ERA and a 5.63 FIP, along with 4.3 walks and 1.5 home runs allowed per nine innings. Meanwhile, the Yankees lead the American League in scoring with nearly 5.6 runs per game. Yankees starter Ryan Yarbrough has turned things around, posting a 2.27 ERA across his last nine starts after a rocky beginning to the 2025 season, during which he split time between the bullpen and rotation.

Pick: Yankees Run Line -1.5 +100 (Greg’s Handicap: Yankees -1.5 -122)

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Greg Peterson
Greg, originally from Wisconsin and a UW Oshkosh alumnus, is widely recognized in the sports media industry, particularly for his expertise in college basketball, which earned him the nickname "Hoops" from Brent Musburger. He has worked with Vanderbilt and Oregon's flagship stations and joined VSIN in 2017. Greg contributes to various channels, hosting "The Baseball Betting Show" and "Coast To Coast Hoops" podcasts, and writes for DK Nation, building on his experience with over 500 articles for the New York Post. Known for his analytical approach, he produces daily spreadsheets for college basketball and MLB games, focusing on educating bettors about the importance of betting on numbers rather than teams.