MLB Picks Today:
Expert baseball handicapper Greg Peterson shares his top MLB picks today for Monday, May 26.
Check out Greg’s Daily MLB Lines and his Baseball Betting Show Podcast. Also, check out our MLB Betting Splits.
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3:05 PM Eastern
St. Louis Cardinals vs. Baltimore Orioles
Cardinals starting pitcher Erick Fedde owns a 3.77 ERA with 0.8 home runs allowed per nine innings and faces an Orioles lineup that entered Sunday ranked 25th in the league in scoring, averaging just over 3.8 runs per game. Orioles starting pitcher Charlie Morton has a 7.86 ERA with 2.0 home runs and 5.3 walks allowed per nine innings.
Pick: Cardinals Moneyline -104 (Greg’s Handicap: Cardinals -144)
4:10 PM Eastern
Cincinnati Reds vs. Kansas City Royals
Royals starting pitcher Michael Lorenzen owns a 3.77 ERA with 1.4 home runs allowed per nine innings, but he’s backed by a bullpen that ranks fifth in bullpen ERA at 3.27. Reds starter Nick Martinez has a 3.43 ERA with just 0.6 home runs allowed per nine innings, though that ERA climbs to 4.18 on the road. The Reds’ overall team ERA of 4.11 ranks 18th.
Pick: Royals Moneyline -116 (Greg’s Handicap: Royals -134)
Chicago White Sox vs. New York Mets
White Sox starter Adrian Houser dazzled in his first MLB start of the season, tossing six shutout innings. Mets starter Clay Holmes draws a favorable matchup against a White Sox lineup that ranks 28th in scoring at 3.3 runs per game — a number that dips to 2.9 on the road. Holmes enters with a 3.13 ERA and just 0.8 home runs allowed per nine innings.
Pick: Under 8.5 Runs (Greg’s Handicapped Total: 7.6)
7:05 PM Eastern
Minnesota Twins vs. Tampa Bay Rays
Twins starter Chris Paddack has allowed three earned runs or fewer in nine straight starts, posting a 2.22 ERA across his last eight. Rays starter Zack Littell holds a 4.25 ERA, but an inflated 5.42 fielding independent and 2.1 home runs allowed per nine innings.
Pick: Twins Moneyline +108 (Greg’s Handicap: Twins -111)
9:38 PM Eastern
New York Yankees vs. Los Angeles Angels
Angels starter Jack Kochanowicz owns a 5.03 ERA and a 5.63 FIP, along with 4.3 walks and 1.5 home runs allowed per nine innings. Meanwhile, the Yankees lead the American League in scoring with nearly 5.6 runs per game. Yankees starter Ryan Yarbrough has turned things around, posting a 2.27 ERA across his last nine starts after a rocky beginning to the 2025 season, during which he split time between the bullpen and rotation.
Pick: Yankees Run Line -1.5 +100 (Greg’s Handicap: Yankees -1.5 -122)
