Player props have become one of baseball’s most entertaining ways to bet, offering value well beyond the moneyline, run line, or game total. Each day, this column highlights the best opportunities on the board — from strikeouts and hits to total bases and pitcher outs recorded — using matchup data, recent form, and betting trends to identify edges. Keep reading for the top MLB player prop picks for April 10. Also, make sure you check out our live VSiN programming for more. Our hosts and analysts will be all over the MLB, which is why it pays to be a VSiN Pro subscriber.
MORE: Check out the VSiN Pro Picks page for more bets from our talented hosts and analysts!
Friday Player Prop Best Bets
Below you’ll find my official plays on the player prop market for Friday. These are the ones that make the VSiN Pro Picks page and count towards my season-long record.
Landen Roupp Over 5.5 Strikeouts (-121) vs. Orioles
Giants at Orioles – 7:15 pm ET
The Orioles have the seventh-highest strikeout rate (25.7%) in baseball this year. They also had the third-highest strikeout rate (24.2%) in MLB last year. That made this a game in which I had to look hard at Roupp, who has been awesome with his swing-and-miss stuff in 2026. Roupp is coming into this one after having struck out seven batters in back-to-back games. He first did it against the Padres on March 30, then he backed it up with another similar performance against the Mets on April 4. Roupp also happened to average 6.17 strikeouts per game against bottom-10 teams in strikeout rate in 2025, so I’ll trust in him to get to the six-K mark tonight.
Kris Bubic Over 17.5 Outs Recorded (-109) vs. White Sox
White Sox at Royals – 7:40 pm ET
I had Seth Lugo to go Over this same exact mark against the White Sox last night, and I’m happy to go back to it with Bubic this evening. The lefty recorded at least 20 outs in three of his five home meetings with bottom-five offenses when looking at batting average in 2025. Well, the White Sox were 27th in MLB in batting average (.232) last year, and they’re back in that same slot with a lower average (.204) this year. Also, only three teams in baseball had a lower wRC+ than Chicago (88) in 2025. And while the White Sox are a little better against southpaws, it’s not significant enough to go away from Bubic. In fact, in Bubic’s one outing against Chicago last season, he pitched 7.0 innings of shutout ball.
Connelly Early Over 5.5 Strikeouts (+134) vs. Cardinals
Red Sox at Cardinals – 8:15 pm ET
Early only had four strikeouts against the Padres last game, but he had six against the Reds on March 29. Most importantly, Early is averaging 92.0 pitches thrown per game this year, which means he has a long leash to work somewhat deep in games. I think that’ll allow him to turn in a good performance against the Cardinals — especially in the strikeout column. Last year, St. Louis had a strikeout rate of 22.0% against lefties, which was higher than the team had against righties. That’s not a miserable number, but it should be good enough for Early to go to work. While he has started somewhat slow as a strikeout pitcher this year, he struck out at least six batters in four of his five starts last year. He was also a high-strikeout hurler in the minors.
Other Best Bets
Jack Kochanowicz Over 3.5 Strikeouts (-120) vs. Reds
Noteworthy OptaAI Player Prop Edges
Check out the BRAND NEW OptaAI Player Props MLB pages for more of these! VSiN Pro subscribers can find 50+ player prop ideas on a daily basis! We’ll list the top edges in some of the biggest markets below, but there will always be a lot more to uncover on the pages themselves.
JT Ginn Over 4.5 Strikeouts (+149) vs. Mets
Our OptaAI player prop projections have him going for 5.45 strikeouts, suggesting these odds should be -174 — a +23.3% edge to the Over.
Joc Pederson Over 0.5 Hits + Runs + RBIs (-137) vs. Yankees
Our OptaAI player prop projections have him finishing with 1.60 HRR, suggesting these odds should be -393 — a +21.9% edge to the Over.
Kerry Carpenter Over 1.5 Total Bases (+133) vs. Marlins
Our OptaAI player prop projections have him finishing with 2.10 total bases, suggesting these odds should be -243 — a +19.2% edge to the Over.
