It’s time for Week 6 of the 2024 NFL season. I strongly suggest you check out the Week 6 NFL Betting Hub, where you’ll find all of the features and picks from my talented co-workers. On top of that, we never stop pumping out good NFL content on our live shows. That’s the beauty of being a subscriber. As a company, we’re relentless in our effort to get you prepared for these games. With that out of the way, let’s get into the fun stuff. Keep reading for my Week 6 NFL best bets and Week 6 NFL predictions.

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2024 NFL Best Bets Record: 15-13 (+3.51 units)

Indianapolis Colts at Tennessee Titans – 1:00 pm ET

I can’t say I feel great about backing the Titans with their current quarterback situation, but this is definitely a favorable spot for Tennessee. The Titans are coming off their bye week, which means they had extra time to work out some issues on offense.

The offensive line play for Tennessee has been a huge concern this season, but this team has some of the best O-Line coaches in the league. So, the team likely made some progress in sorting out the play up front, and this is also the right opponent when it comes to getting things on track there. The Colts’ defensive line has gotten better as the season has progressed, but this was a porous group up front early in the year. That said, look for Tennessee to successfully run the football with Tony Pollard and Tajae Spears.

The Titans should also be able to get the passing game going a little bit. This season, the Colts are just 24th in the NFL in Dropback EPA per play allowed (0.163). This is a very beatable secondary, especially on the outside. So, Calvin Ridley should be able to eat in this game, and I’m not sure it’ll matter who the quarterback is.

It does seem like Will Levis will play here. He has been begging the training staff to let him go after having suffered a shoulder injury two weeks ago. But I should mention that I’m not sure I care who ends up starting under center. While Levis is more talented, he’s also a little more mistake-prone than Mason Rudolph. That said, I’m good with this pick either way.

Tennessee also quietly has the fifth-ranked defense in the league in EPA per play allowed (-0.133), and the team has been good about stopping both the run and the pass. With that in mind, I think the Titans are going to come out fired up and ready to play on that side of the ball. It also sounds like Anthony Richardson will start for Indianapolis in this game. That should be a win for Tennessee. Richardson has all the talent in the world, but Joe Flacco is a better quarterback right now.

Bet: Titans ML (-135 – 2 units)

Los Angeles Chargers at Denver Broncos – 4:05 pm ET

The Broncos are suddenly one of the hottest teams in football, as they come into this one on a three-game winning streak. The reason Denver has turned its season around is that the team is currently tied for second in the league in EPA per play allowed (-0.185). That gives the Broncos a pretty significant defensive edge every single week. The problem with this week is that the team they’re tied with happens to be their opponent. That’s right, Los Angeles’ EPA per play allowed is also -0.185 this season. The Chargers also happen to be coming off a bye week, and they have a much better quarterback than the Broncos.

Jim Harbaugh’s team really should be able to win this one in the Mile High City. The Chargers have had extra time to get a look at Vance Joseph’s defense, so they should be able to find some offensive success here — at least in the early portion of the game, when they can run off some of their game scripts. Also, Los Angeles defensive coordinator Jesse Minter is likely licking his chops about getting to face Bo Nix. While the rookie has played a lot better in recent weeks, we have seen how turnover-prone he can be. I wouldn’t be surprised if the Chargers force several mistakes out of him.

It’s also worth noting that Harbaugh is 14-4-1 against the spread as a road favorite of 7 or less in his NFL career. His teams usually don’t slip up in these spots. Let’s just hope that Herbert can stay healthy here. He is dealing with an injured ankle and is a threat to get knocked out of any game at any given time.

Bet: Chargers -2.5 (-118 – 1.5 units)

Additional Week 6 Best Bets

Greg Joseph Over 6.5 Total Points (+100) vs. Bengals – Click here for my Bengals vs. Giants preview!

Last Week

Vikings ML (-140 – 2 units) vs. Jets
Broncos -2.5 (-115) vs. Raiders

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