Naomi Osaka and Amanda Anisimova will meet in the semifinals of the 2025 US Open on Thursday, September 4th. Osaka advanced to this match by defeating Karolina Muchova in a tough two-set battle, and Anisimova booked her spot with a surprising straight-set win over tournament favorite Iga Swiatek. Now, both of these players are red hot and feeling like they have what it takes to lift this trophy. However, only one of them will be playing in Saturday’s final. That said, let’s get into it with an Osaka vs. Anisimova betting preview.
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Naomi Osaka vs. Amanda Anisimova Odds
Odds from DraftKings Sportsbook accurate as of Wednesday, September 3rd at 11:30 pm ET. Shop around for the best prices!
Moneyline: Osaka -140, Anisimova +110
Spread: Osaka -1.5 Games (-115), Anisimova +1.5 Games (-115)
Total: Over 22.5 Games (-105), Under 22.5 Games (-130)
How To Watch Naomi Osaka vs. Amanda Anisimova
Where: Arthur Ashe Stadium at the USTA Billie Jean King National Tennis Center in Flushing Meadows, New York
When: Thursday, September 4th
Channel: ESPN / ABC
Naomi Osaka vs. Amanda Anisimova Predictions
It’s remarkable that we’re getting a meeting between Osaka and Anisimova in the semifinals. While Osaka is a four-time Grand Slam champion, it’s been quite some time since she looked like a championship-caliber player. Her time away from the sport, whether it was for mental health purposes or maternity leave, understandably did a number on her game. And there were times in which it felt like we’d never see Osaka at this stage of a Grand Slam again. But here we are. Meanwhile, Anisimova also dealt with her own mental demons, leading to some time away from the sport. But we just saw the American in the Wimbledon final, so we know there’s a high-level performer in there. The problem is that Anisimova lost 6-0, 6-0 to Swiatek in that Wimbledon final, and it can be hard to recover from that type of loss. But again, here we are.
We’re now about be treated to a battle between two players with a ton of mental strength, and we’re also going to see two players with outrageous physical strength. Seriously, the ball striking in this match is going to be out of control, and we’re going to see some blistering groundstrokes from both of them.
Osaka appears to be the popular pick to advance to the final, and I can’t say it’s surprising. She is a bigger name, she has accomplished more throughout her career and she has wiped the floor with some good players over the last two weeks — including Coco Gauff. However, at plus-money odds, I’m a little more interested in backing Anisimova.
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This is a match in which both players will be throwing haymakers, and there won’t be a lot of defense. Power will be the name of the game, not mobility or court coverage. But I think Anisimova’s backhand will be the biggest weapon on the court. And if the American is hitting her forehand well, that’ll allow her to match up quite nicely from the back of the court. Anisimova has also been the stronger returner over the last 52 weeks, as her break percentage of 38.2% is a good amount higher than Osaka’s 33.6%. That should help level the playing field with the Osaka serve, which is better than the Anisimova serve — especially when you consider some of the nerves the 27-year-old will be dealing with.
I picked Osaka to beat Gauff a few rounds ago, but I did note that the crowd was my only concern. Osaka clearly disliked playing the role of visitor when she took on Victoria Mboko in Montreal a couple of weeks ago. Gauff just wasn’t in good enough form to do anything about it. Anisimova is.
This New York crowd is going to get behind Anisimova, especially considering the way she lost in that Wimbledon final. I’m interested in seeing how Osaka deals with that, along with an opponent that has the ability to go blow for blow with her from the baseline.
Anisimova also happens to be 2-0 against Osaka. Of course, the two haven’t played one another since 2022, but that history could give Anisimova a little more confidence than she already has. And she’ll need anything she can get with Osaka playing this well.
Bet: Anisimova ML (+112)