The 2026 Miami Open is in full swing at Hard Rock Stadium, and Sunday, March 22 brings another loaded slate of ATP and WTA action from South Florida. We’ve broken down the day’s best tennis betting picks for Miami, digging into matchup tactics, court conditions, and current form to find the sharpest edges on the board. Whether you’re betting the moneyline, game spread, set spread, or total, our 2026 Miami Open best bets are built to help you profit. I’m dropping some of my favorite plays below, but make sure you also monitor the picks page throughout the day. I generally have a few more picks over there, plus I occasionally add plays based on how lines are moving. That’s also where Gill Alexander posts his best bets.
Stefanos Tsitsipas vs. Arthur Fils
Tsitsipas has dropped to No. 51 in the world, plus he’s 0-4 against Fils. That’s why we’re seeing him as a big underdog in this matchup. However, a few of the matches between these two were very tight. Their first actually ended with Fils winning two tiebreakers in a straight-set win, meaning very little came between them. A bunch of the others also saw tiebreakers, or even Tsitsipas winning a set. And one of them ended with Tsitsipas retiring after going down 0-2 in the opening set. With that in mind, I do feel this head-to-head is a little misleading.
It’s also hard not to feel like this is as good a time as any for Tsitsipas to get in the win column. The Greek star just played one of his best matches of the season, posting a TennisViz Performance Rating of 8.6 in a 6-3, 7-6 (3) win over Alex de Minaur. This season has definitely had some ups and downs for Tsitsipas, but he has also been able to stay pretty healthy. On top of that, he has earned three top-10 wins. That said, with Tsitsipas having some big wins under his belt, and not having to deal with any major injuries, perhaps he can keep this momentum going.
Fils has played well since returning from his back injury, but we have seen some poor performances mixed in. Also, just based on my own personal eye test, I don’t think his athleticism and stamina are fully up to speed.
Considering where these two players are right now, I like the idea of taking Tsitsipas at a big plus-money number. His serve should give him a chance to win, and his forehand has the potential to be the biggest weapon on the court. He just has to go out there with some self-belief, but I don’t see why he wouldn’t. Beating de Minaur should give him all the confidence in the world.
Bet: Tsitsipas ML (+141)
Rafael Jodar vs. Tomas Martin Etcheverry
I feel like I haven’t had much success playing Jodar in bigger tournaments this year, which factored into going a little smaller on this than I normally would. However, I do really like this matchup for the Spaniard, and I also like what the betting splits look like. Our VSiN betting splits page shows that Jodar is taking significant money, and it’s never a bad idea to align yourself with smart bettors. However, putting that completely aside, Jodar also has the game to thrive in Miami.
Jodar has already won four matches in South Beach, beating Manas Dhamne and Benjamin Bonzi in qualifying. He then earned a 6-4, 4-6, 6-1 win over Yannick Hanfmann in the Round of 128, then he followed that up with a 6-1, 6-2 win over Aleksandar Vukic. Jodar just has a very big serve, he moves well for a taller player, and he’s a dangerous ball striker — and can hit with some heavy spin. I think everything he does looks a little more effortless than it does with Etcheverry, who plays aggressive tennis but makes more mistakes when looking to go big.
Etcheverry has also played his best tennis on clay recently, which isn’t anything too surprising. But overall, the conditions here look favorable for the 19-year-old. He just needs to handle his nerves with this being one of the bigger matches of his career.
Bet: Jodar ML (-145)
Matteo Berrettini vs. Valentin Vacherot
I have been enjoying the Vacherot experience this year. After shocking the world to win a 1000 towards the end of last season, he has done a good job of proving he’s a legitimate player on the ATP Tour. However, this is a match that I expect Berrettini to win.
These are two players that can really rack up holds in a hurry, but Berrettini is the better server between the two. Berrettini also happens to have one of the biggest forehands on tour, and that shot will be the biggest weapon on the court by a mile. I also like that these are slick, faster-bouncing courts. That means that Berrettini’s backhand, which tends to always be a slice, will get low and force Vacherot to really get down to hit his backhand. That could disrupt the stronger Vacherot wing.
Berrettini also got a look at another big server last round, with his match against Alexander Bublik being one that should help him get ready for Vacherot. Well, Vacherot’s meeting with Mariano Navone won’t serve that same purpose here.
Bet: Berrettini ML (-136)
