Week 6 College Football Betting Splits Systems and Picks:

CFB DK Betting Splits system #1: Going back to the start of the 2022 season, when more than 75% of the handle was on a particular side of an ATS wager, this majority group has gone just 636-698 ATS (47.6%).
System Matches (FADE ALL): WEST VIRGINIA, FLORIDA, RICE, APPALACHIAN STATE, ILLINOIS, OHIO, OHIO STATE, OREGON STATE, MEMPHIS, UTAH, ARIZONA STATE

CFB DK Betting Splits system #2: When 76%+ of the number of bets were on the home side of an ATS wager since the start of the 2022 season, this majority group has gone just 280-297 ATS (48.5%). In 2022 it was 46.5%, in 2023 it was 46.7%, in 2024 it was 46.6%. Last year it was six games over .500.
System Matches (FADE ALL): WEST VIRGINIA, FLORIDA, APPALACHIAN STATE, NORTH TEXAS, WESTERN MICHIGAN, OHIO STATE, MEMPHIS, UTAH, ARIZONA STATE

CFB DK Betting Splits system #3: When the majority of the handle was on road favorites for an ATS wager since the start of the 2022 season, this majority group is just 397-443 ATS (47.3%).
System Matches (FADE ALL): WAKE FOREST, INDIANA, MIAMI (OH), EASTERN MICHIGAN, DUKE, ILLINOIS, OLE MISS, TENNESSEE, LSU, NORTH DAKOTA STATE, JAMES MADISON, BOISE STATE

CFB DK Betting Splits system #4: When a 68%+ majority of the handle was on small home favorites of 7 points or fewer for an ATS wager since the start of the 2023 season, this majority group is 92-73 ATS (55.8%).
System Matches (PLAY ALL): KANSAS STATE, NAVY, OHIO

CFB DK Betting Splits system #5: When a 58% or greater majority of the handle has been on road underdogs for an ATS wager since the start of the 2022 season, this majority group has gone 168-151-2 ATS (52.7%).
System Matches (SLIGHT PLAY ALL): TULANE, BALL STATE, RICE, UCLA, BUFFALO, COASTAL CAROLINA, USC, SYRACUSE

CFB DK Betting Splits system #6: When a majority of 55% or more of number of bets has backed road underdogs for an ATS wager over the past four seasons, this majority group has gone 162-142-1 ATS (53.3%).
System Matches (SLIGHT PLAY ALL): HOUSTON, UCLA, GEORGIA, USC

CFB DK Betting Splits system #8: Contrary to popular belief, majority handle bettors have been very good when getting behind huge home favorites, specifically those favored by 27.5 points or more. In most cases, I would fear this as a prototypical public bet, but these groups are 99-81 ATS (55%) over the last four seasons.
System Matches (PLAY ALL): NORTH TEXAS, NOTRE DAME, OHIO STATE

CFB DK Betting Splits system #10: Since the start of the 2022 season, on games with totals of 49 or lower, 72%+ super majority handle bettors siding with the Under have gone 75-59 (56%).
System Matches (PLAY UNDER ALL): RICE-EAST CAROLINA, OLD DOMINION-APPALACHIAN STATE, MIAMI (OH)-UMASS, DUKE-GEORGIA TECH, ILLINOIS-MICHIGAN STATE, TULSA-NAVY, CENTRAL MICHIGAN-OHIO, KENT STATE-W MICHIGAN, LA LAFAYETTE-LOUISIANA TECH

CFB DK Betting Splits system #11: Since the start of the 2022 season, on games with totals of 46.5 or lower, 72%+ super majority number of bets bettors bucking the low total and siding with the Over have gone 219-186 (54.1%).
System Matches (PLAY OVER ALL): SACRAMENTO STATE-BOWLING GREEN, NORTH CAROLINA-PITTSBURGH, RICE-EAST CAROLINA, OLD DOMINION-APPALACHIAN STATE, CENTRAL MICHIGAN-OHIO

For more Week 6 college football best bets, visit the Week 6 College Football Hub, exclusively at VSiN.com.

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