It’s time for Week 3 of the 2025 NFL season. I strongly suggest you check out the Week 3 NFL Betting Hub, where you’ll find all of the features and picks from my talented co-workers. On top of that, we never stop pumping out good NFL content on our live shows. That’s the beauty of being a subscriber. As a company, we’re relentless in our effort to get you prepared for these games. With that out of the way, let’s get into the fun stuff. Keep reading for my Week 3 NFL best bets and Week 3 NFL player props.
MORE: Check out our Pro Picks page for college football best bets from all of our analysts
New York Jets at Tampa Bay Buccaneers – 1:00 pm ET
Last week, Bucky Irving rushed for 71 yards against the Texans, and he added another 50 yards as a receiver out of the backfield. Freed from having to face an elite Falcons defense, the talented 23-year-old rusher got back to making plays all over the field. Now, Irving has another strong matchup, as Tampa will be facing New York at Raymond James Stadium.
Through two weeks, the Jets are 31st in the NFL in EPA per play allowed (0.214), and they have been miserable against both the run (0.094) and the pass (0.310). With that in mind, even with the Buccaneers being beat up along the offensive line, it’s hard not to like Irving to get himself going.
Hopefully Rachaad White doesn’t cut too much into Irving’s workload, but it shouldn’t doom us even if he does. Irving had 121 yards from scrimmage last week even with White having 65 rushing yards. And that was against a very good Houston defensive front. After doing that, facing New York should be like going against Rick Moranis’ Little Giants defense.
Bet: Irving Over 95.5 Rushing + Receiving Yards (-115)
Los Angeles Rams at Philadelphia Eagles – 1:00 pm ET
The Rams are the NFL’s second-ranked team in EPA per play allowed (-0.130) early in the season, and they have been the league’s best against the pass (-0.148). Of course, it helps that LA got to go against Houston and Tennessee, but the numbers are the numbers. And honestly, the Philadelphia passing game has been in shambles to start the year.
The Eagles might be 2-0 to start the season, but Jalen Hurts has thrown for a total of 253 yards through two weeks. Last week, Hurts’ response to that was to point at the scoreboard in a win over the Chiefs, but that was a game Philadelphia could have lost if Travis Kelce didn’t bobble a ball that turned into an interception on the goal line. Well, if Hurts doesn’t figure things out in a hurry, the Eagles aren’t going to win this game comfortably.
The Rams have the talent and size required to give Saquon Barkley some problems in this game, so there’s a chance LA does a decent job of completely keeping Philadelphia’s offense in check. If that’s the case, the Rams should be able to do enough offensively to give themselves a shot at winning. Let’s not forget that LA was driving with a chance to beat Philadelphia in the NFC Divisional Round last year, and this year’s Rams team is better — and this year’s Eagles team is worse.
Los Angeles is also 17-10-2 against the spread as a road underdog of 7 or less under Sean McVay, and Philadelphia is only 17-17-3 ATS as a favorite of 3.5 to 9.5 under Nick Sirianni.
Bet: Rams +3.5 (-114)
Arizona Cardinals at San Francisco 49ers – 4:25 pm ET
Whether it’s Brock Purdy or Mac Jones under center, the 49ers should be able to move the ball against the Cardinals. Arizona’s defense completely fell apart in a meeting with Carolina last week, and the Cardinals have really just looked as unimpressive as possible in a 2-0 start to the year. The Arizona rushing defense has really been the only strength of the team thus far, but I’m not sure I see the Cards keeping Christian McCaffrey from running well in the 49ers’ first home game of the year.
It’s also hard to imagine this Arizona offense shredding the San Francisco defense. The 49ers are currently fourth in the NFL in EPA per play allowed (-0.105), and they have looked like a much-improved unit with Robert Saleh back calling the shots. Kyler Murray also remains unimpressive as a passer, as he’s outside the Top 15 in Completion Percentage Over Expected (-0.6%) through two weeks.
This is also a revenge spot for San Francisco. In a down 2024 season, Arizona went 2-0 in this head-to-head. Well, the 49ers might not be fully back up, but they’re good enough to get back in the win column against this opponent. Let’s also throw in the fact that Kyle Shanahan is 34-18 straight-up as a home favorite with San Francisco. Meanwhile, Arizona is 4-11 SU as a road underdog under Jonathan Gannon.
Bet: 49ers ML (-137 – 1.5 units)
Dallas Cowboys at Chicago Bears – 4:25 pm ET
This game has shootout written all over it, so it feels like a good spot to find a receiving prop. Well, instead of taking a higher number with CeeDee Lamb, I’ll roll with George Pickens to go Over 52.5 yards. Last week, Pickens hauled in five of his nine targets for 68 yards and a score against the Giants. He and Dak Prescott are starting to develop some chemistry, and this is a good opportunity for him to put up some numbers.
With Jaylon Johnson out indefinitely with a groin injury, Chicago’s group of defensive backs is awful. And Pickens has the luxury of not seeing the opposing team’s best corner to begin with. Look for Pickens to consistently create separation against Tyrique Stevenson, Nick McCloud and Nahshon Wright, and don’t be surprised if Prescott looks his way often.
Bet: Pickens Over 52.5 Receiving Yards (-112)
Additional Week 3 Best Bets
Tyreek Hill Longest Reception Over 23.5 Yards (-115) vs. Bills – CLICK HERE for my Dolphins vs. Bills Thursday Night Football betting preview!
10PT Teaser (-120 at DK – 1.5 units): Steelers +8.5 vs. Patriots, Jaguars +8.5 vs. Texans, Broncos +12.5 vs. Chargers
I’ll likely add more once I dive into the Sunday Night Football and Monday Night Football matchups!
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2025 Record: 10-14 (-4.89 units)
