MLB Picks Today:

Expert baseball handicapper Greg Peterson shares his top MLB picks today for Saturday, September 26.

Check out Greg’s Daily MLB Lines and his Baseball Betting Show Podcast. Also, check out our MLB Betting Splits and tools from our friends at Ballpark Pal, including Strikeout Prop Projections and the MLB YRFI Report.

Our Opta AI MLB Player Prop Projections are also available.

4:05 PM Eastern

New York Mets vs. Washington Nationals

Mets starting pitcher Jonah Tong has a 4.21 ERA this season with 8.8 strikeouts and 4.6 walks per nine innings, with his ERA sitting at 6.29 for his career in a starting role compared to 3.60 out of the bullpen. Nationals starting pitcher Connelly Early has a 3.44 ERA but a much higher 4.60 fielding independent with 1.5 home runs and 3.3 walks per nine innings. He is supported by a bullpen that is 29th in ERA at 5.01, while the lineup is third in scoring with 5.1 runs per game.

Pick: Mets Moneyline -130

Greg’s Handicap: Mets -137

7:10 PM Eastern

Cleveland Guardians vs. Kansas City Royals

Guardians starting pitcher Tanner Bibee is getting a career-low seven strikeouts per nine innings to go with a 4.35 ERA and 1.4 home runs allowed per nine innings. While the Royals offense is last in scoring on the road with 3.6 runs per game, it is seventh at home with nearly 4.9 runs per game. Royals starting pitcher Michael Wacha has a 3.33 ERA but a 4.31 fielding independent with 1.3 home runs per nine innings allowed and only 7.1 strikeouts per nine innings, while being backed up by a bullpen that is 28th in ERA at 5.00.

Pick: Guardians vs. Royals Over 8 Runs

Greg’s Handicap: Total 8.6

Colorado Rockies vs. Chicago White Sox

The Rockies give José Quintana his second start since the beginning of June, and he has a 5.40 ERA with 4.4 strikeouts and 3.6 walks per nine innings while supplying a 5.70 fielding independent. White Sox starting pitcher Davis Martin has a 3.84 ERA with 7.5 strikeouts and 2.8 walks per nine innings and faces a Rockies lineup that is seventh in scoring with over 4.6 runs per game. The White Sox are fifth in scoring with nearly 4.8 runs per game and face a Rockies bullpen that is 27th in ERA at 4.81.

Pick: White Sox Run Line -1.5 -105 and Over 8 Runs

Greg’s Handicap: White Sox -1.5 -118 and Total 8.7

St. Louis Cardinals vs. Milwaukee Brewers

Brewers starting pitcher Dustin May began the season with the Cardinals, so they are familiar with what he is throwing, and the Cardinals are third in road scoring with 5.2 runs per game. May has a 4.67 ERA, while Cardinals starting pitcher Quinn Mathews has a 3.67 ERA with 7.9 strikeouts and 3.7 walks per nine innings. Mathews faces a Brewers lineup that leads the league in scoring at home with 5.6 runs per game, and the Cardinals rank 22nd in bullpen ERA at 4.45.

Pick: Cardinals vs. Brewers Over 7.5 Runs

Greg’s Handicap: Total 8.8

8:40 PM Eastern

Arizona Diamondbacks vs. San Diego Padres

Padres starting pitcher Walker Buehler overall this season has a 4.56 ERA with 1.3 home runs and 3.4 walks per nine innings, but has been at his best of late, as he has allowed three runs or fewer in 12 straight starts. The Diamondbacks’ starting pitcher has made only three starts this season, allowing five home runs across 10 1/3 innings with nine runs allowed in this stretch. The Padres are third in scoring since the All-Star Break with 5.1 runs per game.

Pick: Padres Moneyline -124 and Over 7.5 Runs

Greg’s Handicap: Padres -133 and Total 7.7

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Greg Peterson
Greg, originally from Wisconsin and a UW Oshkosh alumnus, is widely recognized in the sports media industry, particularly for his expertise in college basketball, which earned him the nickname "Hoops" from Brent Musburger. He has worked with Vanderbilt and Oregon's flagship stations and joined VSIN in 2017. Greg contributes to various channels, hosting "The Baseball Betting Show" and "Coast To Coast Hoops" podcasts, and writes for DK Nation, building on his experience with over 500 articles for the New York Post. Known for his analytical approach, he produces daily spreadsheets for college basketball and MLB games, focusing on educating bettors about the importance of betting on numbers rather than teams.